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"Big L" dosage rates.


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11 replies to this topic

#1 Cicolid

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Posted 24 January 2008 - 07:26 AM

Does anyone know from experience what the dosage rates and dosage regime is for "BIG L" ?

I know it is used for gill flukes, but what else is it used for ?

Any advice would be appreciated.

Col

#2 Matthew

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Posted 24 January 2008 - 07:56 AM

1ml per 7L
Used for lots of internal worms really.
Does not work for "wasting disease"

#3 Mintox

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Posted 24 January 2008 - 06:59 PM

(Matthew)
1ml per 7L
Used for lots of internal worms really.
Does not work for "wasting disease"


My new clown loach was wasting away and after adding this stuff it made a recovery by next morning.

As for the OP, you should find useful info in the below link.

http://www.perthcich...ight=levamisole

There's a link some where in there with some guy who seems to know what he's on about.

#4 Matthew

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Posted 25 January 2008 - 08:00 AM

Interesting...
Didn't work for me.
Neither did anything else...

#5 Mintox

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Posted 25 January 2008 - 08:25 PM

(Matthew)
Interesting...
Didn't work for me.
Neither did anything else...


Mine would have been in its very early stages, perhaps yours was well progressed.

#6 the_german

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Posted 26 January 2008 - 07:57 AM

7ml per 40l water is the dosage. nothing else.
50%wc before and after a week 50% again.
redose after 4 weeks.

#7 Mr_docfish

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Posted 28 January 2008 - 01:31 PM

Dosage rate depends on the concentration of the active ingredient being used. Let us know what the concentration is in %w/w or w/v and we can offer the right dose rate. One of the most common mistakes made, unless you know what you are doing.

#8 Noddy65

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Posted 28 January 2008 - 01:50 PM

Have a look on the front Col...I think Big L is 14 g/L Levamisole.

Mike

#9 Mr_docfish

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Posted 28 January 2008 - 02:29 PM

Edited from http://www.loaches.c...hterm=parasites
Recommended Dosage

Dr. Roy Yanong, V.M.D. recommends the following for treating fish with internal parasites susceptible to Levamisole HCL:

In answer to your question, the dosage rate for levamisole in a bath is 2 mg/L (2 ppm) for 24 hours (followed by 70-100% water change, and siphon the bottoms of the tanks), with repeat treatments necessary--retreat in 2-3 weeks, and probably one more time after that. This is regardless of size of fish.

The 2 mg/L dosage rate (of the active ingredient Levamisole) is currently (2007) the level being used by the scientific community. It effectively paralyzes levamisole susceptible parasites at that concentration. Increasing the dosage level does not seem to have any greater effect. Paralysis of the worms takes place when that level of Levamisole HCL is present in the host--your fish. Dr. Yanong recommends that whenever possible, try to diagnose what parasite your fish are harboring prior to treatment. Work with an 'exotic pet' veterinarian, or a fish health specialist to insure you are treating with the right medication.


So if the concentration is 14g/l of active ingredient;
This equals about 1.4ml per 10litres (to give you 2mg/l)
Equals about 1ml per 7litres

The good thing is:
From the same article above
What if I overdose my fish?

The LD-50 (the lethal dose of a compound for 50% of animals exposed) of levamisole is 250 mg/l per 24 hours. This level of dosage is much higher than that which is prescribed for use in a freshwater bath (the method used in our fish tanks). Only extreme overdosing with this medication will result in death to your fish. Few accounts of adverse side effects in aquaria have been noted even with much higher than currently accepted appropriate dosing.


So 7ml per 40litres is still OK, especially if the tank has a high organic load.

Oliver

#10 Cicolid

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Posted 28 January 2008 - 04:05 PM

Thanks for the responses.

Sorry, I just assumed all Big L had the same AI or AC.

The one I have is by "Sykes" Active constituent 14g/L Levamisole.

(Levamisole Hydrochloride 16g/L).

Cheers
Col

#11 Noddy65

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Posted 28 January 2008 - 04:28 PM

Hi Col
As Oliver said above the usual dose for 14gm/l Levamisole is 1 ml / 7 litres of aquarium water.

Olivers link above is terrific. Might be worth making it a sticky actually, what do the mods think?

This is also a useful site (although not specifically about using Levamisole).
http://www.loaches.c...hydrochloride-1

Mike

#12 Mr_docfish

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Posted 28 January 2008 - 05:05 PM

That is the same link that Mintox pointed out (his credit), it is one that I have a kept hard copy of a while back, because it is so good.
A Sticky would be good, thanks Mike, your link is the same as mine, either one would be good to always have on hand.

EOI if you are after 100% Soluble powder of Levamisole HCl ask for me at Aquotix (Wed-Fri) it won't have any other unwanted stuff in it like sugars that encourages bacteria growth. Because you only need a small amount of it, it is quite cheap to have on hand, we treat quite a few fish on arrival with it while in Quarantine (from Overseas, Local and Eastern States).

Oliver




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